Rabbit anti-Human DBF4 Monoclonal Antibody

The antibody against DBF4 was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 1-100 of human DBF4 (Q9UBU7) as the immunogen. The monoclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-15915A

Number

Cat.No	ADA-15915A	Clonality	Monoclonal
Host Species	Rabbit	Target Name	DBF4
Target Synonyms	ASK; CHIF; DBF4A; ZDBF1; DBF4	Form	Liquid
Species Reactivity	Human	Isotype	IgG
Storage Buffer	50% Glycerol, 0.05% BSA, PBS with 0.02% sodium azide, pH7.3.	Purification Method	Affinity purification
Positive Samples	Jurkat, PC-3	Application	ELISA, WB

Cat.No

ADA-15915A

Clonality

Monoclonal

Host Species

Rabbit

Target Name

DBF4

Target Synonyms

ASK; CHIF; DBF4A; ZDBF1; DBF4

Form

Liquid

Species Reactivity

Human

Isotype

IgG

Storage Buffer

50% Glycerol, 0.05% BSA, PBS with 0.02% sodium azide, pH7.3.

Purification Method

Affinity purification

Positive Samples

Jurkat, PC-3

Application

ELISA, WB

Immunogen Description	A synthetic peptide corresponding to a sequence within amino acids 1-100 of human DBF4 (Q9UBU7).	Target Species	Human
Immunogen Sequence	MNSGAMRIHSKGHFQGGIQVKNEKNRPSLKSLKTDNRPEKSKCKPLWGKVFYLDLPSVTISEKLQKDIKDLGGRVEEFLSKDISYLISNKKEAKFAQTLG	Uniprot ID	Q9UBU7

Immunogen Description

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human DBF4 (Q9UBU7).

Target Species

Human

Immunogen Sequence

MNSGAMRIHSKGHFQGGIQVKNEKNRPSLKSLKTDNRPEKSKCKPLWGKVFYLDLPSVTISEKLQKDIKDLGGRVEEFLSKDISYLISNKKEAKFAQTLG

Uniprot ID

Q9UBU7

Background Information

Uniprot Id

Q9UBU7
Target Species

Human
Target Name

DBF4
Target Full Name

Protein DBF4 homolog A
Target Function

Regulatory subunit for CDC7 which activates its kinase activity thereby playing a central role in DNA replication and cell proliferation. Required for progression of S phase. The complex CDC7-DBF4A selectively phosphorylates MCM2 subunit at 'Ser-40' and 'Ser-53' and then is involved in regulating the initiation of DNA replication during cell cycle.
Target Subcellular Location

Nucleus.
Target Tissue Specificity

Highly expressed in testis and thymus. Expressed also in most cancer cells lines.
Target Synonyms

Activator of S phase kinase; ASK; CHIF; Chiffon homolog A; DBF4; DBF4 homolog (S. cerevisiae); DBF4 homolog; DBF4 type zinc finger containing protein 1; DBF4 zinc finger A; DBF4 zinc finger; DBF4; S. cerevisiae; homolog of; DBF4-type zinc finger-containing protein 1; DBF4A; DBF4A_HUMAN; Dumbbell former 4; S. cerevisiae; homolog of; OTTHUMP00000161661; Protein DBF4 homolog A; ZDBF1; Zinc finger; DBF-type containing 1
Target Background

Predicted to enable protein serine/threonine kinase activator activity. Predicted to be involved in positive regulation of nuclear cell cycle DNA replication and regulation of cell cycle phase transition. Located in nuclear body.

Rabbit anti-Human DBF4 Monoclonal Antibody

Specifications

Immunogen Information

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