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Recombinant Human Plexin domain-containing protein 1 (PLXDC1), Truncated

ACP00180

Number
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Specifications


Cat.No ACP00180 Target NamePLXDC1
Target SynonymsTumor endothelial marker 3;Tumor endothelial marker 7FormLiquid or Lyophilized powder
Expression SystemE.coliExpression Range19-426aa
Mol Weight52.9 kDaProtein LengthPartial
PurityGreater than 95% as determined by SDS-PAGE.Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ8IUK5
Background Information
  • Uniprot Id

    Q8IUK5

  • Target Species

    Human

  • Target Name

    PLXDC1

  • Target Full Name

    Plexin domain-containing protein 1

  • Target Function

    Plays a critical role in endothelial cell capillary morphogenesis.

  • Target Subcellular Location

    [Isoform 1]: Cell membrane; Single-pass type I membrane protein. Cell junction, tight junction. Note=Localized predominantly at the tight junctions of vascular endothelial cells and to a lesser extent at the luminal surface of vascular endothelial cells.; [Isoform 2]: Secreted.; [Isoform 3]: Secreted.; [Isoform 4]: Cytoplasm.

  • Target Protein Families

    Plexin family

  • Target Tissue Specificity

    Detected in endothelial cells from colorectal cancer, and in endothelial cells from primary cancers of the lung, liver, pancreas, breast and brain. Not detectable in endothelial cells from normal tissue. Expressed in fibrovascular membrane with increased

  • Target Research Area

    Cardiovascular

  • Target Synonyms

    DKFZp686F0937 ; FLJ36270; FLJ45632; OTTHUMP00000164240; Plexin domain containing 1; Plexin domain containing protein 1 precursor; Plexin domain-containing protein 1; Plxdc1; PXDC1_HUMAN; TEM3; TEM7; Tumor endothelial marker 3; Tumor endothelial marker 7

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