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| Cat.No | ACP04690 | Target Name | SIRPB1 |
|---|---|---|---|
| Target Synonyms | SIRPB1; Signal-regulatory protein beta-1; SIRP-beta-1; CD172 antigen-like family member B; CD antigen CD172b | Form | Liquid or Lyophilized powder |
| Expression System | Yeast | Expression Range | 30-371aa |
| Mol Weight | 39.3kDa | Protein Length | Extracellular Domain |
| Purity | Greater than 90% as determined by SDS-PAGE. | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | O00241 |
|---|
Uniprot Id
O00241
Target Species
Human
Target Name
SIRPB1
Target Full Name
Signal-regulatory protein beta-1
Target Function
Immunoglobulin-like cell surface receptor involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. Participates also in the recruitment of tyrosine kinase SYK. Triggers activation of myeloid cells when associated with TYROBP.
Target Subcellular Location
Cell membrane; Single-pass type I membrane protein.
Target Tissue Specificity
Detected in monocytes and dendritic cells.
Target Research Area
Signal transduction
Target Synonyms
SIRPB1; Signal-regulatory protein beta-1; SIRP-beta-1; CD172 antigen-like family member B; CD antigen CD172b
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