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Recombinant Human Protein MRVI1 (MRVI1), Truncated

ACP05607

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Specifications

Cat.No	ACP05607	Target Name	MRVI1
Target Synonyms	4, 5-trisphosphate receptor-associated cGMP kinase substrate; JAW1-related protein MRVI1, MRVI1; IRAG; JAW1L; Protein MRVI1; Inositol 1	Form	Lyophilized powder
Expression System	Custom Production. Please inquire and provide the desire expression system.	Protein Length	Partial
Purity	>85% (SDS-PAGE)	Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	Q9Y6F6

Background Information

Uniprot Id

Q9Y6F6
Target Species

Human
Target Name

IRAG1
Target Full Name

Inositol 1,4,5-triphosphate receptor associated 1
Target Function

Plays a role as NO/PRKG1-dependent regulator of IP3-induced calcium release; its phosphorylation by PRKG1 inhibits bradykinin and IP3-induced calcium release from intracellular stores. Recruits PRKG1 to the endoplasmic reticulum and may mediate the assembly of PRKG1 and ITPR1 in a macrocomplex. Involved in PRKG1 signaling cascade leading to inhibition of platelet activation and aggregation. Mediates also NO-dependent inhibition of calcium signaling in gastrointestinal smooth muscle contributing to NO-dependent relaxation.
Target Subcellular Location

Cytoplasm, perinuclear region. Sarcoplasmic reticulum. Membrane; Single-pass membrane protein.
Target Tissue Specificity

Expressed in the colon, rectum, and cultured colonic smooth muscle. Detected in various cancer cell lines.
Target Synonyms

MRVI1; IRAG; JAW1L; Protein MRVI1; Inositol 1,4,5-trisphosphate receptor-associated cGMP kinase substrate; JAW1-related protein MRVI1

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Recombinant Human Protein MRVI1 (MRVI1), Truncated

Specifications

Immunogen Information

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