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| Cat.No | ACP06045 | Target Name | UBR3 |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Protein Length | Partial | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q6ZT12 |
|---|
Uniprot Id
Q6ZT12
Target Species
Human
Target Name
UBR3
Target Full Name
E3 ubiquitin-protein ligase UBR3
Target Function
E3 ubiquitin-protein ligase which is a component of the N-end rule pathway. Does not bind to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. May play a role in Shh signaling by mediating the ubiquitination of Kif7. May be important for MYH9 function in certain tissues, possibly by regulating the ubiquitination of MYH9 and consequently affecting its interaction with MYO7A.
Target Subcellular Location
Membrane; Multi-pass membrane protein.
Target Protein Families
UBR1 family
Target Synonyms
DKFZp434P117; DKFZp686N10185; E3 ubiquitin-protein ligase UBR3; FLJ37422; KIAA2024; MGC126489; N-recognin-3; Ubiquitin-protein ligase E3-alpha-3; Ubiquitin-protein ligase E3-alpha-III; Ubr3; UBR3_HUMAN; Zinc finger protein 650; ZNF 650; ZNF650
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