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| Cat.No | ACP06095 | Target Name | LRRC8B |
|---|---|---|---|
| Target Synonyms | LRRC8B; KIAA0231; UNQ6413/PRO21207; Volume-regulated anion channel subunit LRRC8B; Leucine-rich repeat-containing protein 8B; T-cell activation leucine repeat-rich protein; TA-LRRP | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q6P9F7 |
|---|
Uniprot Id
Q6P9F7
Target Species
Human
Target Name
LRRC8B
Target Full Name
Volume-regulated anion channel subunit LRRC8B
Target Function
Non-essential component of the volume-regulated anion channel (VRAC, also named VSOAC channel), an anion channel required to maintain a constant cell volume in response to extracellular or intracellular osmotic changes. The VRAC channel conducts iodide better than chloride and can also conduct organic osmolytes like taurine. Channel activity requires LRRC8A plus at least one other family member (LRRC8B, LRRC8C, LRRC8D or LRRC8E); channel characteristics depend on the precise subunit composition.
Target Subcellular Location
Cell membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane.
Target Protein Families
LRRC8 family
Target Synonyms
LRRC8B; KIAA0231; UNQ6413/PRO21207; Volume-regulated anion channel subunit LRRC8B; Leucine-rich repeat-containing protein 8B; T-cell activation leucine repeat-rich protein; TA-LRRP
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