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| Cat.No | ACP08127 | Target Name | PLPPR4 |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Protein Length | Partial | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q7Z2D5 |
|---|
Uniprot Id
Q7Z2D5
Target Species
Human
Target Name
PLPPR4
Target Full Name
Phospholipid phosphatase-related protein type 4
Target Function
Postsynaptic density membrane protein that indirectly regulates glutamatergic synaptic transmission through lysophosphatidic acid (LPA)-mediated signaling pathways. Binds lysophosphatidic acid (LPA) and mediates its internalization into cells. Could act as receptor or a transporter of this lipid at the post-synaptic membrane. Modulates lysophosphatidic acid (LPA) activity in neuron axonal outgrowth during development by attenuating phospholipid-induced axon collapse.
Target Subcellular Location
Cell junction, synapse, postsynaptic density membrane; Multi-pass membrane protein.
Target Protein Families
PA-phosphatase related phosphoesterase family
Target Tissue Specificity
Expressed by glutamatergic neurons (at protein level).
Target Synonyms
PLPPR4; KIAA0455; LPPR4; PHP1; PRG1; Phospholipid phosphatase-related protein type 4; Brain-specific phosphatidic acid phosphatase-like protein 1; Lipid phosphate phosphatase-related protein type 4; Plasticity-related gene 1 protein; PRG-1
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