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Recombinant Human Proline-rich transmembrane protein 2 (PRRT2), Truncated

ACP08583

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Specifications

Cat.No	ACP08583	Target Name	PRRT2
Target Synonyms	PRRT2; Proline-rich transmembrane protein 2; Dispanin subfamily B member 3; DSPB3	Form	Lyophilized powder
Expression System	Custom Production. Please inquire and provide the desire expression system.	Protein Length	Partial
Purity	>85% (SDS-PAGE)	Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	Q7Z6L0

Background Information

Uniprot Id

Q7Z6L0
Target Species

Human
Target Name

PRRT2
Target Full Name

Proline-rich transmembrane protein 2
Target Function

As a component of the outer core of AMPAR complex, may be involved in synaptic transmission in the central nervous system. In hippocampal neurons, in presynaptic terminals, plays an important role in the final steps of neurotransmitter release, possibly by regulating Ca(2+)-sensing. In the cerebellum, may inhibit SNARE complex formation and downregulate short-term facilitation.
Target Involvement

Episodic kinesigenic dyskinesia 1 (EKD1); Convulsions, familial infantile, with paroxysmal choreoathetosis (ICCA); Seizures, benign familial infantile, 2 (BFIS2)
Target Subcellular Location

Cell membrane; Single-pass membrane protein. Cell junction, synapse, presynaptic cell membrane; Single-pass membrane protein. Cell junction, synapse. Cell projection, axon. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane. Cell junction, synapse, postsynaptic density membrane. Cell projection, dendritic spine.
Target Protein Families

CD225/Dispanin family
Target Synonyms

PRRT2; Proline-rich transmembrane protein 2; Dispanin subfamily B member 3; DSPB3

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Recombinant Human Proline-rich transmembrane protein 2 (PRRT2), Truncated

Specifications

Immunogen Information

Inquire Recombinant Human Proline-rich transmembrane protein 2 (PRRT2), Truncated Now

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