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| Cat.No | ACP09556 | Target Name | LAS1L |
|---|---|---|---|
| Target Synonyms | dJ475B7.2; FLJ12525; FLJ30133; FLJ45274; LAS1 like (S. cerevisiae); Las1 like; LAS1L; LAS1L_HUMAN; Protein LAS1 homolog; Ribosomal biogenesis protein LAS1L; RP3 475B7.2 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-734 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9Y4W2 |
|---|
Uniprot Id
Q9Y4W2
Target Species
Human
Target Name
LAS1L
Target Full Name
Ribosomal biogenesis protein LAS1L
Target Function
Involved in the biogenesis of the 60S ribosomal subunit. Required for maturation of the 28S rRNA. Functions as a component of the Five Friends of Methylated CHTOP (5FMC) complex; the 5FMC complex is recruited to ZNF148 by methylated CHTOP, leading to desumoylation of ZNF148 and subsequent transactivation of ZNF148 target genes.
Target Involvement
Wilson-Turner X-linked mental retardation syndrome (WTS)
Target Subcellular Location
Nucleus, nucleolus. Nucleus, nucleoplasm. Cytoplasm.
Target Protein Families
LAS1 family
Target Synonyms
dJ475B7.2; FLJ12525; FLJ30133; FLJ45274; LAS1 like (S. cerevisiae); Las1 like; LAS1L; LAS1L_HUMAN; Protein LAS1 homolog; Ribosomal biogenesis protein LAS1L; RP3 475B7.2
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