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| Cat.No | ACP10205 | Target Name | CPSF2 |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Expression Range | 1-782 | Protein Length | Full length protein |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9P2I0 |
|---|
Uniprot Id
Q9P2I0
Target Species
Human
Target Name
CPSF2
Target Full Name
Cleavage and polyadenylation specificity factor subunit 2
Target Function
Component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. Involved in the histone 3' end pre-mRNA processing.
Target Subcellular Location
Nucleus.
Target Protein Families
Metallo-beta-lactamase superfamily, RNA-metabolizing metallo-beta-lactamase-like family, CPSF2/YSH1 subfamily
Target Synonyms
Cleavage and polyadenylation specific factor 2; cleavage and polyadenylation specific factor 2; 100kDa; Cleavage and polyadenylation specificity factor 100 kDa subunit; Cleavage and polyadenylation specificity factor subunit 2; CPSF 100 kDa subunit; CPSF 2; CPSF100; Cpsf2; CPSF2_HUMAN; KIAA1367; zgc:92484
Target Background
Predicted to enable RNA binding activity. Involved in mRNA 3'-end processing by stem-loop binding activity and cleavage. Located in membrane. Part of mRNA cleavage and polyadenylation specificity factor complex.
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