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Recombinant Human Huntingtin-interacting protein K (HYPK)

ACP10547

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP10547 Target NameHYPK
Target SynonymsHuntingtin yeast partner K; Huntingtin-interacting protein K; HYPK; HYPK_HUMANFormLyophilized powder
Expression SystemCustom Production. Please inquire and provide the desire expression system.Expression Range1-129
Protein LengthFull length proteinPurity>85% (SDS-PAGE)
Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ9NX55
Background Information
  • Uniprot Id

    Q9NX55

  • Target Species

    Human

  • Target Name

    HYPK

  • Target Full Name

    Huntingtin-interacting protein K

  • Target Function

    Component of several N-terminal acetyltransferase complexes. Inhibits the N-terminal acetylation activity of the N-terminal acetyltransferase NAA10-NAA15 complex (also called the NatA complex). Has chaperone-like activity preventing polyglutamine (polyQ) aggregation of HTT in neuronal cells probably while associated with the NatA complex. May play a role in the NatA complex-mediated N-terminal acetylation of PCNP.

  • Target Subcellular Location

    Nucleus. Cytoplasm.

  • Target Synonyms

    Huntingtin yeast partner K; Huntingtin-interacting protein K; HYPK; HYPK_HUMAN

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