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| Cat.No | ACP10580 | Target Name | SDHAF3 |
|---|---|---|---|
| Target Synonyms | SDHAF3; ACN9; DC11Succinate dehydrogenase assembly factor 3; mitochondrial; SDH assembly factor 3; SDHAF3 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 31-125 |
| Protein Length | Full Length of Mature Protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9NRP4 |
|---|
Uniprot Id
Q9NRP4
Target Species
Human
Target Name
SDHAF3
Target Full Name
Succinate dehydrogenase assembly factor 3, mitochondrial
Target Function
Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Promotes maturation of the iron-sulfur protein subunit SDHB of the SDH catalytic dimer, protecting it from the deleterious effects of oxidants. May act together with SDHAF1.
Target Subcellular Location
Mitochondrion matrix.
Target Protein Families
Complex I LYR family, SDHAF3 subfamily
Target Synonyms
SDHAF3; ACN9; DC11Succinate dehydrogenase assembly factor 3; mitochondrial; SDH assembly factor 3; SDHAF3
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