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| Cat.No | ACP11512 | Target Name | ACTR8 |
|---|---|---|---|
| Target Synonyms | Actin-related protein 8; Actr8; ARP8_HUMAN; hArp8; INO80 complex subunit N | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-624 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9H981 |
|---|
Uniprot Id
Q9H981
Target Species
Human
Target Name
ACTR8
Target Full Name
Actin-related protein 8
Target Function
Plays an important role in the functional organization of mitotic chromosomes. Exhibits low basal ATPase activity, and unable to polymerize.; Proposed core component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair. Required for the recruitment of INO80 (and probably the INO80 complex) to sites of DNA damage. Strongly prefer nucleosomes and H3-H4 tetramers over H2A-H2B dimers, suggesting it may act as a nucleosome recognition module within the complex.
Target Subcellular Location
Nucleus. Chromosome. Note=Specifically localizes to mitotic chromosomes.
Target Protein Families
Actin family, ARP8 subfamily
Target Synonyms
Actin-related protein 8; Actr8; ARP8_HUMAN; hArp8; INO80 complex subunit N
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