Home Products Recombinant Human Lysosomal-trafficking regulator (LYST), Truncated

Recombinant Human Lysosomal-trafficking regulator (LYST), Truncated

ACP12384

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Specifications

Cat.No	ACP12384	Target Name	LYST
Target Synonyms	Beige homolog; beige protein; Chediak-Higashi syndrome 1; CHS; CHS1; Lysosomal-trafficking regulator; LYST; LYST_HUMAN; OTTHUMP00000038327	Form	Lyophilized powder
Expression System	Custom Production. Please inquire and provide the desire expression system.	Protein Length	Partial
Purity	>85% (SDS-PAGE)	Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	Q99698

Background Information

Uniprot Id

Q99698
Target Species

Human
Target Name

LYST
Target Full Name

Lysosomal-trafficking regulator
Target Function

Adapter protein that regulates and/or fission of intracellular vesicles such as lysosomes. Might regulate trafficking of effectors involved in exocytosis. In cytotoxic T-cells and natural killer (NK) cells, has role in the regulation of size, number and exocytosis of lytic granules. In macrophages and dendritic cells, regulates phagosome maturation by controlling the conversion of early phagosomal compartments into late phagosomes. In macrophages and dendritic cells, specifically involved in TLR3- and TLR4-induced production of pro-inflammatory cytokines by regulating the endosomal TLR3- TICAM1/TRIF and TLR4- TICAM1/TRIF signaling pathways
Target Involvement

Chediak-Higashi syndrome (CHS)
Target Subcellular Location

Cytoplasm.
Target Tissue Specificity

Abundantly expressed in adult and fetal thymus, peripheral blood leukocytes, bone marrow and several regions of the adult brain.
Target Synonyms

Beige homolog; beige protein; Chediak-Higashi syndrome 1; CHS; CHS1; Lysosomal-trafficking regulator; LYST; LYST_HUMAN; OTTHUMP00000038327

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Recombinant Human Lysosomal-trafficking regulator (LYST), Truncated

Specifications

Immunogen Information

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