Recombinant Human AT-rich interactive domain-containing protein 3A (ARID3A)

Uniprot Id

Q99856

Target Species

Human

Target Name

ARID3A

Target Full Name

AT-rich interactive domain-containing protein 3A

Target Function

Transcription factor which may be involved in the control of cell cycle progression by the RB1/E2F1 pathway and in B-cell differentiation.

Target Subcellular Location

Nucleus. Cytoplasm. Note=Shuttles between nucleus and cytoplasm.

Target Tissue Specificity

Widely expressed, with highest expression in skeletal muscle, thalamus, and colon.

Target Synonyms

ARI3A_HUMAN; ARID domain containing 3A; ARID domain-containing protein 3A; ARID3A; AT rich interactive domain 3A (BRIGHT- like) protein; AT rich interactive domain 3A (BRIGHT-like); AT rich interactive domain-containing protein 3A; AT-rich interactive domain-containing protein 3A; B cell regulator of IgH transcription; B-cell regulator of IgH transcription; Bright; dead ringer like 1; dead ringer; Drosophila; homolog-like 1; Dead ringer-like protein 1; DRIL1; DRIL3; DRX; E2F binding protein 1; E2F-binding protein 1; E2FBP1; Homo sapiens AT rich interactive domain 3A (BRIGHT-like)

Target Background

This gene encodes a member of the ARID (AT-rich interaction domain) family of DNA binding proteins. It was found by homology to the Drosophila dead ringer gene, which is important for normal embryogenesis. Other ARID family members have roles in embryonic patterning, cell lineage gene regulation, cell cycle control, transcriptional regulation, and possibly in chromatin structure modification.