Home Products Recombinant Human Zinc finger FYVE domain-containing protein 19 (ZFYVE19)

Recombinant Human Zinc finger FYVE domain-containing protein 19 (ZFYVE19)

ACP12899

Number

Order Exclusive Products Now

Request a Quote

High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications

Cat.No	ACP12899	Target Name	ZFYVE19
Form	Lyophilized powder	Expression System	Custom Production. Please inquire and provide the desire expression system.
Expression Range	1-471	Protein Length	Full length protein
Purity	>85% (SDS-PAGE)	Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	Q96K21

Background Information

Uniprot Id

Q96K21
Target Species

Human
Target Name

ZFYVE19
Target Full Name

Abscission/NoCut checkpoint regulator
Target Function

Key regulator of abscission step in cytokinesis: part of the cytokinesis checkpoint, a process required to delay abscission to prevent both premature resolution of intercellular chromosome bridges and accumulation of DNA damage. Together with CHMP4C, required to retain abscission-competent VPS4 (VPS4A and/or VPS4B) at the midbody ring until abscission checkpoint signaling is terminated at late cytokinesis. Deactivation of AURKB results in dephosphorylation of CHMP4C followed by its dissociation from ZFYVE19/ANCHR and VPS4 and subsequent abscission.
Target Involvement

A chromosomal aberration involving ZFYVE19 is associated with acute myeloblastic leukemia (AML). Translocation t(11;15)(q23;q14) with KMT2A/MLL1 (PubMed:12618766).
Target Subcellular Location

Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cleavage furrow. Midbody, Midbody ring.
Target Tissue Specificity

Detected in brain, heart, skeletal muscle, kidney and liver.
Target Synonyms

Abscission/NoCut checkpoint regulator; ANCHR; MLL partner containing FYVE domain; MPFYVE; ZFY19_HUMAN; ZFYVE 19; Zfyve19; Zinc finger FYVE domain containing protein 19; Zinc finger FYVE domain-containing protein 19; Zinc finger FYVE type containing 19; Zinc finger; FYVE domain containing 19

Inquire Recombinant Human Zinc finger FYVE domain-containing protein 19 (ZFYVE19) Now

Full Name *

Business Email Address *

Phone

Products/Services

Catalog Number

Quantity (μg, mg, g, μl, ml, L, kit)

Address

Project Description

AbTriva respects your privacy and protects your personal data in accordance with AbTriva. For more information, please see our data protection statement. *

Submit

Recombinant Human Zinc finger FYVE domain-containing protein 19 (ZFYVE19)

Specifications

Immunogen Information

Inquire Recombinant Human Zinc finger FYVE domain-containing protein 19 (ZFYVE19) Now

Related Products