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| Cat.No | ACP12962 | Target Name | BRF1 |
|---|---|---|---|
| Target Synonyms | 90kD subunit; GTF3B; hBRF; hTFIIIB90; RNA polymerase III; subunit 2; TAF3B2; TAF3C; TAFIII90; TATA box binding protein (TBP) associated factor 3C; TATA box binding protein (TBP) associated factor, 90kD; TF3B_HUMAN; TF3B90; TFIIIB90; Transcription factor IIIB 90 kDa subunit; Transcription initiation factor IIIB, B related factor 1; B-related factor 1; BRF; BRF-1; brf1; BRF1 homolog, GTF3B subunit 2; TATA box-binding protein-associated factor; TBP associated factor, RNA polymerase III, subunit of RNA polymerase III transcription initiation factor IIIB (S. cerevisiae); General transcription factor IIIB | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-677 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q92994 |
|---|
Uniprot Id
Q92994
Target Species
Human
Target Name
BRF1
Target Full Name
Transcription factor IIIB 90 kDa subunit
Target Function
General activator of RNA polymerase which utilizes different TFIIIB complexes at structurally distinct promoters. The isoform 1 is involved in the transcription of tRNA, adenovirus VA1, 7SL and 5S RNA. Isoform 2 is required for transcription of the U6 promoter.
Target Involvement
Cerebellofaciodental syndrome (CFDS)
Target Subcellular Location
Nucleus.
Target Protein Families
TFIIB family
Target Research Area
Epigenetics and Nuclear Signaling
Target Synonyms
B related factor 1; B-related factor 1; BRF; BRF-1; brf1; BRF1 homolog, subunit of RNA polymerase III transcription initiation factor IIIB (S. cerevisiae); General transcription factor IIIB, 90kD subunit; GTF3B; hBRF; hTFIIIB90; RNA polymerase III; subunit 2; TAF3B2; TAF3C; TAFIII90; TATA box binding protein (TBP) associated factor 3C; TATA box binding protein (TBP) associated factor, RNA polymerase III, GTF3B subunit 2; TATA box-binding protein-associated factor; TBP associated factor, RNA polymerase III, 90kD; TF3B_HUMAN; TF3B90; TFIIIB90; Transcription factor IIIB 90 kDa subunit; Transcription initiation factor IIIB
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