Home Products Recombinant Human Cell division cycle-associated 7-like protein (CDCA7L)

Recombinant Human Cell division cycle-associated 7-like protein (CDCA7L)

ACP13204

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Specifications

Cat.No	ACP13204	Target Name	CDCA7L
Target Synonyms	c Myc Interacting protein JPO2; CDA7L_HUMAN; Cdca7l; Cell division cycle-associated 7-like protein; DKFZp762L0311; HR1; JPO2; Protein JPO2; R1; RAM2; Transcription factor RAM2	Form	Lyophilized powder
Expression System	Custom Production. Please inquire and provide the desire expression system.	Expression Range	1-454
Protein Length	Full length protein	Purity	>85% (SDS-PAGE)
Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	Q96GN5

Background Information

Uniprot Id

Q96GN5
Target Species

Human
Target Name

CDCA7L
Target Full Name

Cell division cycle-associated 7-like protein
Target Function

Plays a role in transcriptional regulation as a repressor that inhibits monoamine oxidase A (MAOA) activity and gene expression by binding to the promoter. Plays an important oncogenic role in mediating the full transforming effect of MYC in medulloblastoma cells. Involved in apoptotic signaling pathways; May act downstream of P38-kinase and BCL-2, but upstream of CASP3/caspase-3 as well as CCND1/cyclin D1 and E2F1.
Target Subcellular Location

Cytoplasm. Nucleus. Note=Associates with chromatin. Translocates from cytoplasm to nucleus under dexamethasone induction.
Target Tissue Specificity

Ubiquitous. Overexpressed in medulloblastoma.
Target Synonyms

c Myc Interacting protein JPO2; CDA7L_HUMAN; Cdca7l; Cell division cycle-associated 7-like protein; DKFZp762L0311; HR1; JPO2; Protein JPO2; R1; RAM2; Transcription factor RAM2
Target Background

Acts upstream of or within positive regulation of cell population proliferation. Located in cytosol; fibrillar center; and nucleoplasm.

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Recombinant Human Cell division cycle-associated 7-like protein (CDCA7L)

Specifications

Immunogen Information

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