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Recombinant Human Kinesin-like protein KIF18A (KIF18A), Truncated

ACP13337

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP13337 Target NameKIF18A
FormLyophilized powderExpression SystemCustom Production. Please inquire and provide the desire expression system.
Protein LengthPartialPurity>85% (SDS-PAGE)
Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ8NI77
Background Information
  • Uniprot Id

    Q8NI77

  • Target Species

    Human

  • Target Name

    KIF18A

  • Target Full Name

    Kinesin-like protein KIF18A

  • Target Function

    Microtubule-depolymerizing kinesin which plays a role in chromosome congression by reducing the amplitude of preanaphase oscillations and slowing poleward movement during anaphase, thus suppressing chromosome movements. May stabilize the CENPE-BUB1B complex at the kinetochores during early mitosis and maintains CENPE levels at kinetochores during chromosome congression.

  • Target Subcellular Location

    Cell projection, ruffle. Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.

  • Target Protein Families

    TRAFAC class myosin-kinesin ATPase superfamily, Kinesin family

  • Target Synonyms

    AU024633; B130001M12Rik; DKFZp434G2226 ; KI18A_HUMAN; KIF 18A; KIF18A; kinesin family member 18A; Kinesin like protein KIF18A; Kinesin-like protein KIF18A; Marrow stromal KIF18A; MGC27627; MS KIF18A; MS-KIF18A; RGD1561740; RP23 206C1.1

  • Target Background

    KIF18A is a member of the kinesin superfamily of microtubule-associated molecular motors (see MIM 148760) that use hydrolysis of ATP to produce force and movement along microtubules (Luboshits and Benayahu, 2005 [PubMed 15878648]).

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