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Recombinant Human GrpE protein homolog 2, mitochondrial (GRPEL2)

ACP14826

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP14826 Target NameGRPEL2
Target SynonymsGrpE like 2; mitochondrial; GrpE protein homolog 2; GRPE2_HUMAN; GRPEL 2; Grpel2; mitochondrial; Mt GrpE#2; Mt-GrpE#2FormLyophilized powder
Expression SystemCustom Production. Please inquire and provide the desire expression system.Expression Range33-225
Protein LengthFull Length of Mature ProteinPurity>85% (SDS-PAGE)
Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ8TAA5
Background Information
  • Uniprot Id

    Q8TAA5

  • Target Species

    Human

  • Target Name

    GRPEL2

  • Target Full Name

    GrpE protein homolog 2, mitochondrial

  • Target Function

    Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Seems to control the nucleotide-dependent binding of mitochondrial HSP70 to substrate proteins. Stimulates ATPase activity of mt-HSP70. May also serve to modulate the interconversion of oligomeric (inactive) and monomeric (active) forms of mt-HSP70.

  • Target Subcellular Location

    Mitochondrion matrix.

  • Target Protein Families

    GrpE family

  • Target Synonyms

    GrpE like 2; mitochondrial; GrpE protein homolog 2; GRPE2_HUMAN; GRPEL 2; Grpel2; mitochondrial; Mt GrpE#2; Mt-GrpE#2

  • Target Background

    Predicted to enable adenyl-nucleotide exchange factor activity and unfolded protein binding activity. Predicted to be involved in protein import into mitochondrial matrix. Located in mitochondrion.

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