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Recombinant Human Extracellular sulfatase Sulf-2 (SULF2), Truncated

ACP15188

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Specifications

Cat.No	ACP15188	Target Name	SULF2
Target Synonyms	Extracellular sulfatase Sulf 2; Extracellular sulfatase Sulf-2; HSulf-2; HSulf2; Sulf2; SULF2_HUMAN	Form	Lyophilized powder
Expression System	Custom Production. Please inquire and provide the desire expression system.	Protein Length	Partial
Purity	>85% (SDS-PAGE)	Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	Q8IWU5

Background Information

Uniprot Id

Q8IWU5
Target Species

Human
Target Name

SULF2
Target Full Name

Extracellular sulfatase Sulf-2
Target Function

Exhibits arylsulfatase activity and highly specific endoglucosamine-6-sulfatase activity. It can remove sulfate from the C-6 position of glucosamine within specific subregions of intact heparin.
Target Subcellular Location

Endoplasmic reticulum. Golgi apparatus, Golgi stack. Cell surface.
Target Protein Families

Sulfatase family
Target Tissue Specificity

Expressed at highest levels in the ovary, skeletal muscle, stomach, brain, uterus, heart, kidney and placenta.
Target Synonyms

Extracellular sulfatase Sulf 2; Extracellular sulfatase Sulf-2; HSulf-2; HSulf2; Sulf2; SULF2_HUMAN
Target Background

Heparan sulfate proteoglycans (HSPGs) act as coreceptors for numerous heparin-binding growth factors and cytokines and are involved in cell signaling. Heparan sulfate 6-O-endosulfatases, such as SULF2, selectively remove 6-O-sulfate groups from heparan sulfate. This activity modulates the effects of heparan sulfate by altering binding sites for signaling molecules (Dai et al., 2005 [PubMed 16192265]).

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Recombinant Human Extracellular sulfatase Sulf-2 (SULF2), Truncated

Specifications

Immunogen Information

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