Recombinant Human Histone H1oo (H1FOO)

Uniprot Id

Q8IZA3

Target Species

Human

Target Name

H1-8

Target Full Name

Histone H1.8

Target Function

May play a key role in the control of gene expression during oogenesis and early embryogenesis, presumably through the perturbation of chromatin structure. Essential for meiotic maturation of germinal vesicle-stage oocytes. The somatic type linker histone H1c is rapidly replaced by H1oo in a donor nucleus transplanted into an oocyte. The greater mobility of H1oo as compared to H1c may contribute to this rapid replacement and increased instability of the embryonic chromatin structure. The rapid replacement of H1c with H1oo may play an important role in nuclear remodeling.

Target Subcellular Location

Cytoplasm. Nucleus. Chromosome.

Target Protein Families

Histone H1/H5 family

Target Tissue Specificity

Oocyte-specific.

Target Synonyms

dJ221C16.2; dJ221C16.5; DmeH1; H1 0 histone ; H1; H1 histone family member 0; H1 histone family member 1; H1 histone family member 3 ; H1 histone family member 5; H1 histone family member N testis specific; H1 histone family member O oocyte specific; H1 histone family member X; H1(0); H1.1; H1.2; H1.3; H1.4; H1.5; H10; H1A; H1f0; H1F0 protein; H1F1; H1F2; H1F3; H1F4; H1F5; H1FNT; H1FOO; H1FOO protein; H1FOO_HUMAN; H1FT; H1FV; H1FX; H1oo; H1t; H1T2; H1X; HANP1; His1; HisC; HIST1; HIST1H1A; HIST1H1B; HIST1H1C; HIST1H1D; HIST1H1E; HIST1H1T; Histone 1 H1a; Histone 1 H1b; Histone 1 H1c; Histone 1 H1d; Histone 1 H1e; Histone 1 H1t; Histone; Histone H1' ; Histone H1.0; Histone H1.1; Histone H1.2; Histone H1.3; Histone H1.4; Histone H1.5; Histone H1oo; Histone H1x; MGC116819; MGC126630; MGC126632; MGC126642; MGC138176; MGC138345; MGC15959; MGC3992; MGC50807; MGC5241; MGC8350; Oocyte specific histone H1; Oocyte specific linker histone H1; Oocyte-specific histone H1; Oocyte-specific linker histone H1; osH1; Testicular H1 histone