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| Cat.No | ACP15342 | Target Name | SESTD1 |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Expression Range | 1-696 | Protein Length | Full length protein |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q86VW0 |
|---|
Uniprot Id
Q86VW0
Target Species
Human
Target Name
SESTD1
Target Full Name
SEC14 domain and spectrin repeat-containing protein 1
Target Function
May act as the primary docking protein directing membrane turnover and assembly of the transient receptor potential channels TRPC4 and TRPC5. Binds phospholipids such as phosphatidylinositol monophosphates, phosphatidylinositol diphosphates (PIP2s) and phosphatidic acid, but not less polar lipids including phosphatidylcholine, phosphatidylserine, and phosphatidylinositol. The binding to PIP2s is calcium dependent. Might be involved in the plasma membrane localization of CTNNB1.
Target Protein Families
SOLO family
Target Tissue Specificity
Broad expression. High expression in thalamus and brain. Significantly expressed in vasculature.
Target Synonyms
huntingtin interacting protein like protein; Huntingtin-interacting protein-like protein; Protein Solo; SEC14 and spectrin domains 1; SEC14 domain and spectrin repeat-containing protein 1; SESD1_HUMAN; sestd1; SOLO
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