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Recombinant Human N-terminal EF-hand calcium-binding protein 2 (NECAB2)

ACP15371

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP15371 Target NameNECAB2
FormLyophilized powderExpression SystemCustom Production. Please inquire and provide the desire expression system.
Expression Range1-386Protein LengthFull length protein
Purity>85% (SDS-PAGE)Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ7Z6G3
Background Information
  • Uniprot Id

    Q7Z6G3

  • Target Species

    Human

  • Target Name

    NECAB2

  • Target Full Name

    N-terminal EF-hand calcium-binding protein 2

  • Target Function

    May act as a signaling scaffold protein that senses intracellular calcium. Can modulate ligand-induced internalization of ADORA2A and coupling efficiency of mGluR5/GRM5; for both receptors may regulate signaling activity such as promoting MAPK1/3 (ERK1/2) activation.

  • Target Subcellular Location

    Cytoplasm. Cell projection, dendrite. Cell projection, axon. Cell membrane.

  • Target Tissue Specificity

    Expressed in brain. Expressed in the spinal dorsal horn with especially strong expression in lamina IIi; found in excitory synaptic boutons and in ependymal cells (at protein level).

  • Target Synonyms

    EF hand calcium binding protein 2; EF-hand calcium-binding protein 2; N-terminal EF-hand calcium-binding protein 2; NECA2_HUMAN; Necab2; Neuronal calcium binding protein 2; Neuronal calcium-binding protein 2; Stip 2 ; Stip-2; Stip2 ; Synaptotagmin interacting protein 2; Synaptotagmin-interacting protein 2

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