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| Cat.No | ACP15387 | Target Name | GPHB5 |
|---|---|---|---|
| Target Synonyms | GPHB5; GPB5; ZLUT1Glycoprotein hormone beta-5; Thyrostimulin subunit beta | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 25-130 |
| Protein Length | Full Length of Mature Protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q86YW7 |
|---|
Uniprot Id
Q86YW7
Target Species
Human
Target Name
GPHB5
Target Full Name
Glycoprotein hormone beta-5
Target Function
Functions as a heterodimeric glycoprotein hormone with GPHA2 able to bind and activate the thyroid-stimulating hormone receptor (TSHR), leading to increased cAMP production. Plays a central role in controlling thyroid cell metabolism.
Target Subcellular Location
Secreted.
Target Protein Families
Glycoprotein hormones subunit beta family
Target Tissue Specificity
Highly expressed in brain and at low levels in pituitary. Also found in retina, testis and skin but not in pancreas, parotid, kidney, stomach, liver, colon, small intestine, thyroid, brain or adrenal gland. In pituitary, colocalizes with ACTH, suggesting
Target Synonyms
GPHB5; GPB5; ZLUT1Glycoprotein hormone beta-5; Thyrostimulin subunit beta
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