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| Cat.No | ACP15638 | Target Name | EVC2 |
|---|---|---|---|
| Target Synonyms | EVC2; LBN; Limbin; Ellis-van Creveld syndrome protein 2; EVC2 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q86UK5 |
|---|
Uniprot Id
Q86UK5
Target Species
Human
Target Name
EVC2
Target Full Name
Limbin
Target Function
Component of the EvC complex that positively regulates ciliary Hedgehog (Hh) signaling. Plays a critical role in bone formation and skeletal development. May be involved in early embryonic morphogenesis.
Target Involvement
Ellis-van Creveld syndrome (EVC); Acrofacial dysostosis, Weyers type (WAD)
Target Subcellular Location
Cell membrane; Single-pass type I membrane protein. Cytoplasm, cytoskeleton, cilium basal body. Cell projection, cilium. Cell projection, cilium membrane. Nucleus.
Target Tissue Specificity
Found in the heart, placenta, lung, liver, skeletal muscle, kidney and pancreas.
Target Synonyms
EVC2; LBN; Limbin; Ellis-van Creveld syndrome protein 2; EVC2
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