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| Cat.No | ACP15643 | Target Name | SETD3 |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Expression Range | 1-594 | Protein Length | Full length protein |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q86TU7 |
|---|
Uniprot Id
Q86TU7
Target Species
Human
Target Name
SETD3
Target Full Name
Actin-histidine N-methyltransferase
Target Function
Protein-histidine N-methyltransferase that specifically mediates 3-methylhistidine (tele-methylhistidine) methylation of actin at 'His-73'. Histidine methylation of actin is required for smooth muscle contraction of the laboring uterus during delivery. Does not have protein-lysine N-methyltransferase activity and probably only catalyzes histidine methylation of actin.
Target Subcellular Location
Cytoplasm. Nucleus.
Target Protein Families
Class V-like SAM-binding methyltransferase superfamily, Histone-lysine methyltransferase family, SETD3 subfamily
Target Synonyms
C14orf154; Chromosome 14 open reading frame 154 ; DKFZp761E1415; FLJ23027; Histone lysine N methyltransferase setd3; Histone-lysine N-methyltransferase setd3; MGC87236; SET domain containing 3; SET domain containing protein 3; SET domain-containing protein 3; SETD 3; Setd3; SETD3_HUMAN
Target Background
Enables protein-L-histidine N-tele-methyltransferase activity. Involved in actin modification and peptidyl-histidine methylation. Located in cytoplasm.
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