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| Cat.No | ACP15661 | Target Name | RAI1 |
|---|---|---|---|
| Target Synonyms | RAI1; KIAA1820; Retinoic acid-induced protein 1 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q7Z5J4 |
|---|
Uniprot Id
Q7Z5J4
Target Species
Human
Target Name
RAI1
Target Full Name
Retinoic acid-induced protein 1
Target Function
Transcriptional regulator of the circadian clock components: CLOCK, ARNTL/BMAL1, ARNTL2/BMAL2, PER1/3, CRY1/2, NR1D1/2 and RORA/C. Positively regulates the transcriptional activity of CLOCK a core component of the circadian clock. Regulates transcription through chromatin remodeling by interacting with other proteins in chromatin as well as proteins in the basic transcriptional machinery. May be important for embryonic and postnatal development. May be involved in neuronal differentiation.
Target Involvement
Smith-Magenis syndrome (SMS)
Target Subcellular Location
Cytoplasm. Nucleus.
Target Tissue Specificity
Expressed in all tissues examined with higher expression in the heart and brain. No expression was seen in the corpus callosum of the brain.
Target Synonyms
RAI1; KIAA1820; Retinoic acid-induced protein 1
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