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| Cat.No | ACP15864 | Target Name | TFAP2E |
|---|---|---|---|
| Target Synonyms | TFAP2ETranscription factor AP-2-epsilon; AP2-epsilon; Activating enhancer-binding protein 2-epsilon | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-442 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q6VUC0 |
|---|
Uniprot Id
Q6VUC0
Target Species
Human
Target Name
TFAP2E
Target Full Name
Transcription factor AP-2-epsilon
Target Function
Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. AP-2-epsilon may play a role in the development of the CNS and in cartilage differentiation.
Target Subcellular Location
Nucleus.
Target Protein Families
AP-2 family
Target Tissue Specificity
Expressed in skin, primary keratinocytes, immortalized keratinocytes, and HeLa cell line.
Target Synonyms
TFAP2ETranscription factor AP-2-epsilon; AP2-epsilon; Activating enhancer-binding protein 2-epsilon
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