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Recombinant Human Neutral cholesterol ester hydrolase 1 (NCEH1), Truncated

ACP16558

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Specifications

Cat.No	ACP16558	Target Name	NCEH1
Target Synonyms	Arylacetamide deacetylase like 1; Arylacetamide deacetylase-like 1; NCEH; Nceh1; NCEH1_HUMAN; Neutral cholesterol ester hydrolase 1; Neutral cholesterol ester hydrolase	Form	Lyophilized powder
Expression System	Custom Production. Please inquire and provide the desire expression system.	Protein Length	Partial
Purity	>85% (SDS-PAGE)	Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	Q6PIU2

Background Information

Uniprot Id

Q6PIU2
Target Species

Human
Target Name

NCEH1
Target Full Name

Neutral cholesterol ester hydrolase 1
Target Function

Hydrolyzes 2-acetyl monoalkylglycerol ether, the penultimate precursor of the pathway for de novo synthesis of platelet-activating factor. May be responsible for cholesterol ester hydrolysis in macrophages. Also involved in organ detoxification by hydrolyzing exogenous organophosphorus compounds. May contribute to cancer pathogenesis by promoting tumor cell migration.
Target Subcellular Location

Cell membrane; Single-pass type II membrane protein. Microsome.
Target Protein Families

'GDXG' lipolytic enzyme family
Target Tissue Specificity

Expressed in monocyte-derived macrophages. Up-regulated in invasive melanoma and breast carcinoma cell lines.
Target Synonyms

Arylacetamide deacetylase like 1; Arylacetamide deacetylase-like 1; NCEH; Nceh1; NCEH1_HUMAN; Neutral cholesterol ester hydrolase 1; Neutral cholesterol ester hydrolase
Target Background

Predicted to enable hydrolase activity. Predicted to be involved in ether lipid metabolic process. Predicted to act upstream of or within SMAD protein signal transduction; protein dephosphorylation; and xenobiotic metabolic process. Located in membrane.

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Recombinant Human Neutral cholesterol ester hydrolase 1 (NCEH1), Truncated

Specifications

Immunogen Information

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