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| Cat.No | ACP17685 | Target Name | BMT2 |
|---|---|---|---|
| Target Synonyms | C7orf60; CG060_HUMAN; DKFZp762M126; FLJ31818; UPF0532 protein C7orf60 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-405 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q1RMZ1 |
|---|
Uniprot Id
Q1RMZ1
Target Species
Human
Target Name
SAMTOR
Target Full Name
S-adenosylmethionine sensor upstream of mTORC1
Target Function
S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 signaling. Probably also acts as a S-adenosyl-L-methionine-dependent methyltransferase (Potential)
Target Protein Families
BMT2 family
Target Synonyms
C7orf60; CG060_HUMAN; DKFZp762M126; FLJ31818; UPF0532 protein C7orf60
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