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| Cat.No | ACP17974 | Target Name | TARBP1 |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Protein Length | Partial | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q13395 |
|---|
Uniprot Id
Q13395
Target Species
Human
Target Name
TARBP1
Target Full Name
Probable methyltransferase TARBP1
Target Function
Probable S-adenosyl-L-methionine-dependent methyltransferase which methylates RNA molecules such as tRNAs.; (Microbial infection) In case of infection by HIV-1, it binds to the loop region of TAR RNA, a region also bound by RNA polymerase II. Binding of TARBP1 and RNA polymerase II to HIV-1 TAR RNA is mutually exclusive, suggesting that TARBP1 may function alone or in conjunction with HIV-1 Tat to disengage RNA polymerase II from HIV-1 TAR RNA.
Target Protein Families
Class IV-like SAM-binding methyltransferase superfamily, RNA methyltransferase TrmH family
Target Synonyms
FLJ30482; Probable methyltransferase TARBP1; TAR (HIV) RNA binding protein 1; TAR; TAR RNA loop binding protein; TAR RNA-binding protein 1; TAR RNA-binding protein of 185 kDa; TARB1_HUMAN; TARBP1; TRM3; TRP-185; TRP185
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