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| Cat.No | ACP18132 | Target Name | HERC3 |
|---|---|---|---|
| Target Synonyms | HERC3; KIAA0032Probable E3 ubiquitin-protein ligase HERC3; EC 2.3.2.26; HECT domain and RCC1-like domain-containing protein 3; HECT-type E3 ubiquitin transferase HERC3 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q15034 |
|---|
Uniprot Id
Q15034
Target Species
Human
Target Name
HERC3
Target Full Name
Probable E3 ubiquitin-protein ligase HERC3
Target Function
E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.
Target Subcellular Location
Cytoplasm. Cytoplasmic vesicle. Note=Also found in vesicular-like structures.
Target Synonyms
HERC3; KIAA0032Probable E3 ubiquitin-protein ligase HERC3; EC 2.3.2.26; HECT domain and RCC1-like domain-containing protein 3; HECT-type E3 ubiquitin transferase HERC3
Target Background
This gene encodes a member the HERC ubiquitin ligase family. The encoded protein is located in the cytosol and binds ubiquitin via a HECT domain. Mutations in this gene have been associated with colorectal and gastric carcinomas. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
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