Recombinant Human Sp110 nuclear body protein (SP110)

Cat.No	ACP19027	Target Name	SP110
Form	Lyophilized powder	Expression System	Custom Production. Please inquire and provide the desire expression system.
Expression Range	1-689	Protein Length	Full length protein
Purity	>85% (SDS-PAGE)	Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Cat.No

ACP19027

Target Name

SP110

Form

Lyophilized powder

Expression System

Custom Production. Please inquire and provide the desire expression system.

Expression Range

1-689

Protein Length

Full length protein

Purity

>85% (SDS-PAGE)

Storage Buffer

5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Target Species	Human	Uniprot ID	Q9HB58

Background Information

Uniprot Id

Q9HB58
Target Species

Human
Target Name

SP110
Target Full Name

Sp110 nuclear body protein
Target Function

Transcription factor. May be a nuclear hormone receptor coactivator. Enhances transcription of genes with retinoic acid response elements (RARE).
Target Involvement

Hepatic venoocclusive disease with immunodeficiency (VODI)
Target Subcellular Location

Nucleus. Note=Found in the nuclear body.
Target Tissue Specificity

Highly expressed in peripheral blood leukocytes and spleen. Detected at intermediate levels in thymus, prostate, testis, ovary, small intestine and colon, and at low levels in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.
Target Synonyms

FLJ22835; IFI 41; IFI 75; IFI41; IFI75; Interferon induced protein 41 30kD; Interferon induced protein 41; Interferon induced protein 41/75; Interferon induced protein 75 52kD; Interferon induced protein 75; Interferon-induced protein 41/75; IPR 1; IPR1; Phosphoprotein 41; Phosphoprotein 75; SP 110; SP110; Sp110 nuclear body protein; SP110_HUMAN; Speckled 110 kDa; Transcriptional coactivator Sp110; VODI
Target Background

The nuclear body is a multiprotein complex that may have a role in the regulation of gene transcription. This gene is a member of the SP100/SP140 family of nuclear body proteins and encodes a leukocyte-specific nuclear body component. The protein can function as an activator of gene transcription and may serve as a nuclear hormone receptor coactivator. In addition, it has been suggested that the protein may play a role in ribosome biogenesis and in the induction of myeloid cell differentiation. Alternative splicing has been observed for this gene and three transcript variants, encoding distinct isoforms, have been identified.

Recombinant Human Sp110 nuclear body protein (SP110)

Specifications

Immunogen Information

Inquire Recombinant Human Sp110 nuclear body protein (SP110) Now

Related Products