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| Cat.No | ACP19978 | Target Name | PRSS37 |
|---|---|---|---|
| Target Synonyms | PRSS37; TRYX2; Probable inactive serine protease 37; Probable inactive trypsin-X2 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 20-235 |
| Protein Length | Full Length of Mature Protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | A4D1T9 |
|---|
Uniprot Id
A4D1T9
Target Species
Human
Target Name
PRSS37
Target Full Name
Probable inactive serine protease 37
Target Function
Plays a role in male fertility. May have a role in sperm migration or binding to zona-intact eggs. Involved in the activation of the proacrosin/acrosin system.
Target Involvement
Patients with unexplained male infertility (UMI) show a decrease in the number of sperm cells compared to fertile men (PubMed:27649891). Sperm exhibit also abnormal activation of the proacrosin/acrosin system and premature proteolysis of ADAM2 (PubMed:27649891).
Target Subcellular Location
Cytoplasmic vesicle, secretory vesicle, acrosome. Secreted.
Target Protein Families
Peptidase S1 family
Target Tissue Specificity
Testis-specific. Expressed in spermatids (at protein level).
Target Synonyms
PRSS37; TRYX2; Probable inactive serine protease 37; Probable inactive trypsin-X2
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