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Recombinant Human Nuclear export mediator factor NEMF (NEMF), Truncated

ACP20597

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP20597 Target NameNEMF
Target Synonyms1500011I12Rik; 4933405E14Rik; Antigen NY-CO-1; FLJ10051 ; Nemf; NEMF_HUMAN; Nuclear export mediator factor Nemf; NY CO 1; SDCCAG1; SDCG1; Serologically defined colon cancer antigen 1FormLyophilized powder
Expression SystemCustom Production. Please inquire and provide the desire expression system.Protein LengthPartial
Purity>85% (SDS-PAGE)Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDO60524
Background Information
  • Uniprot Id

    O60524

  • Target Species

    Human

  • Target Name

    NEMF

  • Target Full Name

    Ribosome quality control complex subunit NEMF

  • Target Function

    Component of the ribosome quality control complex (RQC), a ribosome-associated complex that mediates ubiquitination and extraction of incompletely synthesized nascent chains for proteasomal degradation. NEMF is responsible for selective recognition of stalled 60S subunits by recognizing an exposed, nascent chain-conjugated tRNA moiety. NEMF is important for the stable association of LTN1 to the complex. May indirectly play a role in nuclear export.

  • Target Subcellular Location

    Nucleus.

  • Target Protein Families

    NEMF family

  • Target Tissue Specificity

    Expressed in brain, heart, liver, lung, spleen, and skeletal muscle. Also expressed at lower levels in stomach and testis.

  • Target Synonyms

    1500011I12Rik; 4933405E14Rik; Antigen NY-CO-1; FLJ10051 ; Nemf; NEMF_HUMAN; Nuclear export mediator factor Nemf; NY CO 1; SDCCAG1; SDCG1; Serologically defined colon cancer antigen 1

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