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| Cat.No | ACP22159 | Target Name | SNRPC |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Expression Range | 1-159 | Protein Length | Full length protein |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | P09234 |
|---|
Uniprot Id
P09234
Target Species
Human
Target Name
SNRPC
Target Full Name
U1 small nuclear ribonucleoprotein C
Target Function
Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region.
Target Subcellular Location
Nucleus.
Target Protein Families
U1 small nuclear ribonucleoprotein C family
Target Synonyms
FLJ20302; OTTHUMP00000016238; OTTMUSP00000026897; RU1C_HUMAN; Small nuclear ribonucleoprotein polypeptide C; Snrpc; U1 C; U1 small nuclear ribonucleoprotein 1C; U1 small nuclear ribonucleoprotein C; U1 small nuclear RNP specific C; U1 snRNP C; U1 snRNP protein C; U1-C; U1C; U1C protein; Yhc1
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