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| Cat.No | ACP22820 | Target Name | AFF1 |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Protein Length | Partial | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | P51825 |
|---|
Uniprot Id
P51825
Target Species
Human
Target Name
AFF1
Target Full Name
AF4/FMR2 family member 1
Target Involvement
A chromosomal aberration involving AFF1 is associated with acute leukemias. Translocation t(4;11)(q21;q23) with KMT2A/MLL1. The result is a rogue activator protein.
Target Subcellular Location
Nucleus.
Target Protein Families
AF4 family
Target Synonyms
AF 4; AF 4 protein; AF4; AF4-MLL; AF4/FMR2 family member 1; AFF 1; AFF1; AFF1_HUMAN; ALL1 fused gene from chromosome 4; ALL1-fused gene from chromosome 4 protein; FEL; MGC134969; MLL/AF4; MLLT2; myeloid/lymphoid or mixed lineage leukemia (trithorax homolog; Drosophila); translocated to; 2; MYELOID/LYMPHOID OR MIXED LINEAGE LEUKEMIA TRANSLOCATED TO 2; MLLT2; PBM1; Pre B cell monocytic leukemia partner 1; Protein AF-4; Protein FEL; Proto-oncogene AF4
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