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| Cat.No | ACP22836 | Target Name | BLVRA |
|---|---|---|---|
| Target Synonyms | BIEA_HUMAN; Biliverdin IX alpha reductase; Biliverdin reductase A; Biliverdin-IX alpha-reductase; BLVR A; BLVR; Blvra; BVR A; BVR; BVRA; Zinc metalloprotein | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-296 |
| Protein Length | Full length | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | P53004 |
|---|
Uniprot Id
P53004
Target Species
Human
Target Name
BLVRA
Target Full Name
Biliverdin reductase A
Target Function
Reduces the gamma-methene bridge of the open tetrapyrrole, biliverdin IX alpha, to bilirubin with the concomitant oxidation of a NADH or NADPH cofactor.
Target Involvement
Hyperbiliverdinemia (HBLVD)
Target Subcellular Location
Cytoplasm.
Target Protein Families
Gfo/Idh/MocA family, Biliverdin reductase subfamily
Target Tissue Specificity
Liver.
Target Research Area
Signal Transduction
Target Synonyms
BIEA_HUMAN; Biliverdin IX alpha reductase; Biliverdin reductase A; Biliverdin-IX alpha-reductase; BLVR A; BLVR; Blvra; BVR A; BVR; BVRA; Zinc metalloprotein
Target Background
The protein encoded by this gene belongs to the biliverdin reductase family, members of which catalyze the conversion of biliverdin to bilirubin in the presence of NADPH or NADH. Mutations in this gene are associated with hyperbiliverdinemia. Alternatively spliced transcript variants have been found for this gene.
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