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| Cat.No | ACP23070 | Target Name | ACOT2 |
|---|---|---|---|
| Target Synonyms | ACOT2; PTE2; PTE2AAcyl-coenzyme A thioesterase 2; mitochondrial; Acyl-CoA thioesterase 2; EC 3.1.2.2; Acyl-coenzyme A thioester hydrolase 2a; CTE-Ia; Long-chain acyl-CoA thioesterase 2; ZAP128 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | P49753 |
|---|
Uniprot Id
P49753
Target Species
Human
Target Name
ACOT2
Target Full Name
Acyl-coenzyme A thioesterase 2, mitochondrial
Target Function
Catalyzes the hydrolysis of acyl-CoAs into free fatty acids and coenzyme A (CoASH), regulating their respective intracellular levels. Displays higher activity toward long chain acyl CoAs (C14-C20). The enzyme is involved in enhancing the hepatic fatty acid oxidation in mitochondria.
Target Subcellular Location
Mitochondrion.
Target Protein Families
C/M/P thioester hydrolase family
Target Tissue Specificity
Strongest expression in heart, liver, muscle and kidney. Weak in placenta and pancreas.
Target Synonyms
ACOT2; PTE2; PTE2AAcyl-coenzyme A thioesterase 2; mitochondrial; Acyl-CoA thioesterase 2; EC 3.1.2.2; Acyl-coenzyme A thioester hydrolase 2a; CTE-Ia; Long-chain acyl-CoA thioesterase 2; ZAP128
Target Background
This gene encodes a member of the acyl-CoA thioesterase protein family, and is one of four acyl-CoA hydrolase genes located in a cluster on chromosome 14. Alternative splicing results in multiple transcript variants.
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