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Recombinant Human Peroxiredoxin-5, mitochondrial (PRDX5)

ACP23552

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP23552 Target NamePRDX5
FormLyophilized powderExpression SystemCustom Production. Please inquire and provide the desire expression system.
Expression Range53-214Protein LengthFull Length of Mature Protein
Purity>85% (SDS-PAGE)Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDP30044
Background Information
  • Uniprot Id

    P30044

  • Target Species

    Human

  • Target Name

    PRDX5

  • Target Full Name

    Peroxiredoxin-5, mitochondrial

  • Target Function

    Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events.

  • Target Subcellular Location

    [Isoform Mitochondrial]: Mitochondrion.; [Isoform Cytoplasmic+peroxisomal]: Cytoplasm. Peroxisome matrix.

  • Target Protein Families

    Peroxiredoxin family, Prx5 subfamily

  • Target Tissue Specificity

    Widely expressed.

  • Target Synonyms

    ACR1; Alu co repressor 1; Alu corepressor 1; Antioxidant enzyme B166; AOEB166; B166; epididymis secretory protein Li 55; HEL-S-55; Liver tissue 2D-page spot 71B; mitochondrial; Peroxiredoxin 5; mitochondrial; Peroxiredoxin V; Peroxiredoxin-5; Peroxisomal antioxidant enzyme; PLP; PMP20; PRDX 5; PRDX5; PRDX5_HUMAN; PRDX6; Prx-V; PRXV; SBBI10; Thioredoxin peroxidase PMP20; Thioredoxin reductase; TPx type VI

  • Target Background

    This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein interacts with peroxisome receptor 1 and plays an antioxidant protective role in different tissues under normal conditions and during inflammatory processes. The use of alternate transcription start sites is thought to result in transcript variants that use different in-frame translational start codons to generate isoforms that are targeted to the mitochondrion (isoform L) or peroxisome/cytoplasm (isoform S). Multiple related pseudogenes have been defined for this gene.

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