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Rabbit anti-Human ARFIP2 Polyclonal Antibody

The antibody against ARFIP2 was raised in rabbit using the Human ARFIP2 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC, IF.

ADC-54089A

The antibody against ARFIP2 was raised in rabbit using the Human ARFIP2 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC, IF.

$600.00

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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ADC-54089A ClonalityPolyclonal
Host SpeciesRabbitTarget NameARFIP2
FormLiquidSpecies ReactivityHuman, Mouse, Rat
IsotypeIgGStorage Buffer50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.02% sodium azide
Purification MethodAntigen affinity purifiedConjugateNon-conjugated
ApplicationELISA, IF, IHC, WBStorageUpon receipt

Immunogen Information


Immunogen DescriptionHuman ARFIP2Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDP53365
Background Information
  • Uniprot Id

    P53365

  • Target Species

    Human

  • Target Name

    ARFIP2

  • Target Full Name

    Arfaptin-2

  • Target Function

    Plays a role in constitutive metalloproteinase (MMP) secretion from the trans Golgi network. May have important functions during vesicle biogenesis at certain cargo subdomains, which could be predominantly utilized by secreted MMPs, such as MMP7 and MMP2. Also involved in autophagy by regulating the starvation-dependent trafficking of ATG9A vesicles which deliver the phosphatidylinositol 4-kinase beta (PI4KB) to the autophagosome initiation site. In addition, plays a role in NF-kappa-B inhibition by interacting with IKBKB and IKBKG.

  • Target Subcellular Location

    Golgi apparatus. Golgi apparatus, trans-Golgi network membrane.

  • Target Synonyms

    ADP ribosylation factor interacting protein 2; ADP-ribosylation factor-interacting protein 2; Arfaptin 2; Arfaptin-2; ARFIP2; ARFP2_HUMAN; FLJ18046; FLJ18697; FLJ99239; Partner of RAC1; POR1; Protein POR1

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