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Rabbit anti-Human GTF2E2 Polyclonal Antibody

The antibody against GTF2E2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-291 of human GTF2E2 (NP_002086.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-01117A

The antibody against GTF2E2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-291 of human GTF2E2 (NP_002086.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

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Specifications


Cat.No ADA-01117A ClonalityPolyclonal
Host SpeciesRabbitTarget NameGTF2E2
Target SynonymsFE; TTD6; TF2E2; TFIIE-B; GTF2E2FormLiquid
Species ReactivityHuman, Mouse, RatIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.02% sodium azide, pH7.3.Purification MethodAffinity purification
Positive SamplesMouse testis, RajiApplicationELISA, WB

Immunogen Information


Immunogen DescriptionRecombinant fusion protein containing a sequence corresponding to amino acids 1-291 of human GTF2E2 (NP_002086.1).Target SpeciesHuman
Uniprot IDP29084Immunogen Sequence
Background Information
  • Uniprot Id

    P29084

  • Target Species

    Human

  • Target Name

    GTF2E2

  • Target Full Name

    Transcription initiation factor IIE subunit beta

  • Target Function

    Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.

  • Target Involvement

    Trichothiodystrophy 6, non-photosensitive (TTD6)

  • Target Subcellular Location

    Nucleus.

  • Target Protein Families

    TFIIE beta subunit family

  • Target Research Area

    Transcription

  • Target Synonyms

    FE; General transcription factor IIE subunit 2; General transcription factor IIE; polypeptide 2; beta 34kDa ; gtf2e2; T2EB_HUMAN; TF2E 2; TF2E2; TFIIE B; TFIIE-beta; Transcription initiation factor IIE beta subunit; Transcription initiation factor IIE subunit beta

  • Target Background

    The general transcription factor IIE (TFIIE) is part of the RNA polymerase II transcription initiation complex, recruiting TFIIH and being essential for promoter clearance by RNA polymerase II. TFIIE is a heterodimer (and sometimes heterotetramer) of alpha and beta subunits. The protein encoded by this gene represents the beta subunit of TFIIE.

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