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The antibody against SMEK1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 395-594 of human SMEK1 (NP_001271210.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.
The antibody against SMEK1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 395-594 of human SMEK1 (NP_001271210.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.
| Cat.No | ADA-01244A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | SMEK1 |
| Target Synonyms | smk1; FLFL1; PP4R3; SMEK1; smk-1; PP4R3A; MSTP033; KIAA2010 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | HeLa, Rat brain, HepG2, Jurkat, MCF-7, Mouse spleen | Application | ELISA, WB, IHC-P |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 395-594 of human SMEK1 (NP_001271210.1). | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | VQTFKGLKLRFEQQRERQDNPKLDSMRSILRNHRYRRDARTLEDEEEMWFNTDEDDMEDGEAVVSPSDKTKNDDDIMDPISKFMERKKLKESEEKEVLLKTNLSGRQSPSFKLSLSSGTKTNLTSQSSTTNLPGSPGSPGSPGSPGSPGSVPKNTSQTAAITTKGGLVGLVDYPDDDEDDDEDEDKEDTLPLSKKAKFDS | Uniprot ID | Q6IN85 |
Uniprot Id
Q6IN85
Target Species
Human
Target Name
PPP4R3A
Target Full Name
Serine/threonine-protein phosphatase 4 regulatory subunit 3A
Target Function
Regulatory subunit of serine/threonine-protein phosphatase 4. May regulate the activity of PPP4C at centrosomal microtubule organizing centers. The PPP4C-PPP4R2-PPP4R3A PP4 complex specifically dephosphorylates H2AX phosphorylated on 'Ser-140' (gamma-H2AX) generated during DNA replication and required for DNA DSB repair.
Target Subcellular Location
Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Nucleus. Note=In interphase localized in the cytoplasm and in the nucleus (with higher levels). During metaphase located in pericentriolar regions.
Target Protein Families
SMEK family
Target Synonyms
FLFL1; KIAA2010; MEK1 SUPPRESSOR 1; MSTP033; P4R3A_HUMAN; PP4R3 ALPHA; PP4R3; PP4R3A; PPP4R3A; Protein phosphatase 4 regulatory subunit 3A; PROTEIN PHOSPHATASE 4, REGULATORY SUBUNIT 3, ALPHA; Serine/threonine-protein phosphatase 4 regulatory subunit 3A; SMEK homolog 1; SMEK homolog 1, suppressor of mek1 (Dictyostelium); smek1; Smk 1; SMK1
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