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Rabbit anti-Human PFDN6 Polyclonal Antibody

The antibody against PFDN6 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-129 of human PFDN6 (NP_055075.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-01642A

The antibody against PFDN6 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-129 of human PFDN6 (NP_055075.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

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Specifications


Cat.No ADA-01642A ClonalityPolyclonal
Host SpeciesRabbitTarget NamePFDN6
Target SynonymsHKE2; KE-2; PFD6; H2-KE2; PFDN6FormLiquid
Species ReactivityMouseIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.02% sodium azide, pH7.3.Purification MethodAffinity purification
Positive SamplesMouse liverApplicationELISA, WB

Immunogen Information


Immunogen DescriptionRecombinant fusion protein containing a sequence corresponding to amino acids 1-129 of human PFDN6 (NP_055075.1).Target SpeciesHuman
Immunogen SequenceMAELIQKKLQGEVEKYQQLQKDLSKSMSGRQKLEAQLTENNIVKEELALLDGSNVVFKLLGPVLVKQELGEARATVGKRLDYITAEIKRYESQLRDLERQSEQQRETLAQLQQEFQRAQAAKAGAPGKAUniprot IDO15212
Background Information
  • Uniprot Id

    O15212

  • Target Species

    Human

  • Target Name

    PFDN6

  • Target Full Name

    Prefoldin subunit 6

  • Target Function

    Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.

  • Target Protein Families

    Prefoldin subunit beta family

  • Target Synonyms

    H2 KE2; H2KE2; HKE2; HLA class II region expressed gene KE2; KE 2; KE2; KE2 protein; KE2, mouse, homolog of; PFD6_HUMAN; Pfdn6; Prefoldin subunit 6; Protein Ke2

  • Target Background

    PFDN6 is a subunit of the heteromeric prefoldin complex that chaperones nascent actin (see MIM 102560) and alpha- and beta-tubulin (see MIM 602529 and MIM 191130, respectively) chains pending their transfer to the cytosolic chaperonin containing TCP1 (MIM 186980) (CCT) complex (Hansen et al., 1999 [PubMed 10209023]).

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