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The antibody against ADSS was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human ADSS (NP_001117.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, IF/ICC, ELISA.
The antibody against ADSS was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human ADSS (NP_001117.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, IF/ICC, ELISA.
| Cat.No | ADA-02350A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | ADSS |
| Target Synonyms | ADEH; ADSS; ADSS 2 | Form | Liquid |
| Species Reactivity | Human, Mouse | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | 293T, Mouse brain, Mouse lung | Application | ELISA, WB, IF/ICC, IHC-P |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human ADSS (NP_001117.2). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | P30520 | Immunogen Sequence |
Uniprot Id
P30520
Target Species
Human
Target Name
ADSS2
Target Full Name
Adenylosuccinate synthetase isozyme 2
Target Function
Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.
Target Subcellular Location
Cytoplasm. Mitochondrion. Note=Partially associated with particulate fractions.
Target Protein Families
Adenylosuccinate synthetase family
Target Synonyms
ADSS2; ADSS; Adenylosuccinate synthetase isozyme 2; AMPSase 2; AdSS 2; EC 6.3.4.4; Adenylosuccinate synthetase; acidic isozyme; Adenylosuccinate synthetase; liver isozyme; L-type adenylosuccinate synthetase; IMP--aspartate ligase 2
Target Background
This gene encodes the enzyme adenylosuccinate synthetase which catalyzes the first committed step in the conversion of inosine monophosphate to adenosine monophosphate. A pseudogene of this gene is found on chromosome 17.
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