Rabbit anti-Human PTH2R Polyclonal Antibody

The antibody against PTH2R was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 27-145 of human PTH2R (NP_005039.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-04014A

Number

Cat.No	ADA-04014A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	PTH2R
Target Synonyms	PTHR2; PTH2R	Form	Liquid
Species Reactivity	Human	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.02% sodium azide, pH7.3.	Purification Method	Affinity purification
Positive Samples	BxPC-3, LO2	Application	ELISA, WB

Cat.No

ADA-04014A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

PTH2R

Target Synonyms

PTHR2; PTH2R

Form

Liquid

Species Reactivity

Human

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.02% sodium azide, pH7.3.

Purification Method

Affinity purification

Positive Samples

BxPC-3, LO2

Application

ELISA, WB

Immunogen Description	Recombinant fusion protein containing a sequence corresponding to amino acids 27-145 of human PTH2R (NP_005039.1).	Target Species	Human
Immunogen Sequence	DSDGTITIEEQIVLVLKAKVQCELNITAQLQEGEGNCFPEWDGLICWPRGTVGKISAVPCPPYIYDFNHKGVAFRHCNPNGTWDFMHSLNKTWANYSDCLRFLQPDISIGKQEFFERLY	Uniprot ID	P49190

Immunogen Description

Recombinant fusion protein containing a sequence corresponding to amino acids 27-145 of human PTH2R (NP_005039.1).

Target Species

Human

Immunogen Sequence

DSDGTITIEEQIVLVLKAKVQCELNITAQLQEGEGNCFPEWDGLICWPRGTVGKISAVPCPPYIYDFNHKGVAFRHCNPNGTWDFMHSLNKTWANYSDCLRFLQPDISIGKQEFFERLY

Uniprot ID

P49190

Background Information

Uniprot Id

P49190
Target Species

Human
Target Name

PTH2R
Target Full Name

Parathyroid hormone 2 receptor
Target Function

This is a specific receptor for parathyroid hormone. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. PTH2R may be responsible for PTH effects in a number of physiological systems. It may play a significant role in pancreatic function. PTH2R presence in neurons indicates that it may function as a neurotransmitter receptor.
Target Subcellular Location

Cell membrane; Multi-pass membrane protein.
Target Protein Families

G-protein coupled receptor 2 family
Target Tissue Specificity

Expressed abundantly in brain and pancreas. Also expressed in the testis.
Target Research Area

Neuroscience
Target Synonyms

Parathyroid hormone 2 receptor; Parathyroid hormone receptor precursor ; PTH 2 receptor ; PTH2 receptor; Pth2r; PTH2R_HUMAN; Pthr 2; Pthr2
Target Background

The protein encoded by this gene is a member of the G-protein coupled receptor 2 family. This protein is a receptor for parathyroid hormone (PTH). This receptor is more selective in ligand recognition and has a more specific tissue distribution compared to parathyroid hormone receptor 1 (PTHR1). It is activated only by PTH and not by parathyroid hormone-like hormone (PTHLH) and is particularly abundant in brain and pancreas. Alternative splicing results in multiple transcript variants.

Rabbit anti-Human PTH2R Polyclonal Antibody

Specifications

Immunogen Information

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