Rabbit anti-Human FOXD3 Polyclonal Antibody

The antibody against FOXD3 was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 322-335AA of human FOXD3 as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB.

ADA-04235A

Number

Cat.No	ADA-04235A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	FOXD3
Target Synonyms	AIS1; HFH2; VAMAS2; Genesis; FOXD3	Form	Liquid
Species Reactivity	Human, Mouse	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.02% sodium azide, pH7.3.	Purification Method	Affinity purification
Positive Samples	HeLa	Application	WB

Cat.No

ADA-04235A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

FOXD3

Target Synonyms

AIS1; HFH2; VAMAS2; Genesis; FOXD3

Form

Liquid

Species Reactivity

Human, Mouse

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.02% sodium azide, pH7.3.

Purification Method

Affinity purification

Positive Samples

HeLa

Application

Immunogen Description	A synthetic peptide corresponding to a sequence within amino acids 322-335AA of human FOXD3.	Target Species	Human
Immunogen Sequence	Complete sequences for the immunogen, target protein, and peptides are available upon request.	Uniprot ID	Q9UJU5

Immunogen Description

A synthetic peptide corresponding to a sequence within amino acids 322-335AA of human FOXD3.

Target Species

Human

Immunogen Sequence

Complete sequences for the immunogen, target protein, and peptides are available upon request.

Uniprot ID

Q9UJU5

Background Information

Uniprot Id

Q9UJU5
Target Species

Human
Target Name

FOXD3
Target Full Name

Forkhead box protein D3
Target Function

Binds to the consensus sequence 5'-A[AT]T[AG]TTTGTTT-3' and acts as a transcriptional repressor. Also acts as a transcriptional activator. Promotes development of neural crest cells from neural tube progenitors. Restricts neural progenitor cells to the neural crest lineage while suppressing interneuron differentiation. Required for maintenance of pluripotent cells in the pre-implantation and peri-implantation stages of embryogenesis.
Target Involvement

Autoimmune disease 1 (AIS1)
Target Subcellular Location

Nucleus.
Target Tissue Specificity

Expressed in chronic myeloid leukemia, Jurkat T-cell leukemia and teratocarcinoma cell lines, but not in any other cell lines or normal tissues examined.
Target Synonyms

AIS1; forkhead box D3; Forkhead box protein D3; foxd3; FOXD3_HUMAN; Genesis; HFH2; HNF3/FH transcription factor genesis; VAMAS2
Target Background

This gene belongs to the forkhead family of transcription factors which is characterized by a distinct forkhead domain. Mutations in this gene cause autoimmune susceptibility 1.

Rabbit anti-Human FOXD3 Polyclonal Antibody

Specifications

Immunogen Information

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