Rabbit anti-Human SDHAF2 Polyclonal Antibody

The antibody against SDHAF2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-166 of human SDHAF2 (NP_060311.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-04565A

Number

Cat.No	ADA-04565A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	SDHAF2
Target Synonyms	PGL2; SDH5; hSDH5; C11orf79; SDHAF2	Form	Liquid
Species Reactivity	Human, Mouse	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.01% thimerosal, pH7.3.	Purification Method	Affinity purification
Positive Samples	HeLa, Mouse kidney, Mouse brain, Mouse stomach	Application	ELISA, WB

Cat.No

ADA-04565A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

SDHAF2

Target Synonyms

PGL2; SDH5; hSDH5; C11orf79; SDHAF2

Form

Liquid

Species Reactivity

Human, Mouse

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.01% thimerosal, pH7.3.

Purification Method

Affinity purification

Positive Samples

HeLa, Mouse kidney, Mouse brain, Mouse stomach

Application

ELISA, WB

Immunogen Description	Recombinant fusion protein containing a sequence corresponding to amino acids 1-166 of human SDHAF2 (NP_060311.1).	Target Species	Human
Immunogen Sequence	MAVSTVFSTSSLMLALSRHSLLSPLLSVTSFRRFYRGDSPTDSQKDMIEIPLPPWQERTDESIETKRARLLYESRKRGMLENCILLSLFAKEHLQHMTEKQLNLYDRLINEPSNDWDIYYWATEAKPAPEIFENEVMALLRDFAKNKNKEQRLRAPDLEYLFEKPR	Uniprot ID	Q9NX18

Immunogen Description

Recombinant fusion protein containing a sequence corresponding to amino acids 1-166 of human SDHAF2 (NP_060311.1).

Target Species

Human

Immunogen Sequence

MAVSTVFSTSSLMLALSRHSLLSPLLSVTSFRRFYRGDSPTDSQKDMIEIPLPPWQERTDESIETKRARLLYESRKRGMLENCILLSLFAKEHLQHMTEKQLNLYDRLINEPSNDWDIYYWATEAKPAPEIFENEVMALLRDFAKNKNKEQRLRAPDLEYLFEKPR

Uniprot ID

Q9NX18

Background Information

Uniprot Id

Q9NX18
Target Species

Human
Target Name

SDHAF2
Target Full Name

Succinate dehydrogenase assembly factor 2, mitochondrial
Target Function

Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SDHA of the SDH catalytic dimer.
Target Involvement

Paragangliomas 2 (PGL2)
Target Subcellular Location

Mitochondrion matrix.
Target Protein Families

SDHAF2 family
Target Synonyms

Chromosome 11 open reading frame 79; FLJ20487; hSDH5; mitochondrial; Paraganglioma or familial glomus tumors 2; PGL2; SDH assembly factor 2; SDH5; Sdhaf2; SDHF2_HUMAN; Succinate dehydrogenase assembly factor 2, mitochondrial; Succinate dehydrogenase subunit 5
Target Background

This gene encodes a mitochondrial assembly factor needed for the flavination of a succinate dehydrogenase complex subunit (SDHA), which is required for activity of the succinate dehydrogenase complex. Mutations in this gene are associated with paraganglioma.

Rabbit anti-Human SDHAF2 Polyclonal Antibody

Specifications

Immunogen Information

Inquire Rabbit anti-Human SDHAF2 Polyclonal Antibody Now

Related Products