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Rabbit anti-Human HOXB13 Polyclonal Antibody

The antibody against HOXB13 was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 50-150 of human HOXB13 (NP_006352.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-04843A

The antibody against HOXB13 was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 50-150 of human HOXB13 (NP_006352.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

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Specifications


Cat.No ADA-04843A ClonalityPolyclonal
Host SpeciesRabbitTarget NameHOXB13
Target SynonymsHPC9; PSGD; HOXB13FormLiquid
Species ReactivityHuman, Mouse, RatIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.01% thimerosal, pH7.3.Purification MethodAffinity purification
Positive SamplesHeLa, DU145, HT-29, Mouse small intestine, Rat small intestineApplicationELISA, WB

Immunogen Information


Immunogen DescriptionA synthetic peptide corresponding to a sequence within amino acids 50-150 of human HOXB13 (NP_006352.2).Target SpeciesHuman
Immunogen SequencePLDLPGSAEPPKQCHPCPGVPQGTSPAPVPYGYFGGGYYSCRVSRSSLKPCAQAATLAAYPAETPTAGEEYPSRPTEFAFYPGYPGTYQPMASYLDVSVVQUniprot IDQ92826
Background Information
  • Uniprot Id

    Q92826

  • Target Species

    Human

  • Target Name

    HOXB13

  • Target Full Name

    Homeobox protein Hox-B13

  • Target Function

    Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Binds preferentially to methylated DNA.

  • Target Involvement

    Prostate cancer (PC)

  • Target Subcellular Location

    Nucleus.

  • Target Protein Families

    Abd-B homeobox family

  • Target Synonyms

    Homeo box B13; Homeobox B13; Homeobox protein Hox B13; Homeobox protein Hox-B13; Homeobox protein HoxB13; HOX B13; HOXB 13; HOXB13; HXB13_HUMAN; PSGD; PSGD protein

  • Target Background

    This gene encodes a transcription factor that belongs to the homeobox gene family. Genes of this family are highly conserved among vertebrates and essential for vertebrate embryonic development. This gene has been implicated to play a role in fetal skin development and cutaneous regeneration. In mice, a similar gene was shown to exhibit temporal and spatial colinearity in the main body axis of the embryo, but was not expressed in the secondary axes, which suggests functions in body patterning along the axis. This gene and other HOXB genes form a gene cluster at chromosome the 17q21-22 region.

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